International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - 10(3), February, 2018

Pages: 10-14

Date of Publication: 01-Feb-2018


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Management of Congenitally Missing Bilateral Lateral Incisors with Fixed Orthodontic Treatment, Ridge Augmentation and Two Stage Implant Therapy: Multidisciplinary Approach \? A Case Report

Author: T. Ramakrishnan, Saravanan Pushparajan, Rathna, R. Vijayalakshmi

Category: Healthcare

Abstract:Aim: Placing dental implants in the esthetic zone is considered to be the ultimate challenge for many dentists. Insufficient bone is a common problem for implant placement, especially in the upper anterior jaw. A multidisciplinary approach towards the replacement of congenitally missing lateral incisors was planned.
Case Report: Orthodontic treatment was done to create adequate space to place implant in relation to upper right and left lateral incisors. Insufficient ridge width was confirmed by a computerized tomography scan in relation to 22 region, which was augmented at the time of implant placement. Two stage implant was placed in relation to upper right and left lateral incisors. Permanent restoration was placed after 4 months.
Conclusion: This case report describes esthetic and functional outcomes obtained by the multidisciplinary approach for the restoration of congenitally missing maxillary left and right lateral incisor areas.

Keywords: Dental Implants, Orthodontics, Ridge Augmentation

DOI: 10.7324/IJCRR.2017.1033

Full Text:

INTRODUCTION
The successful use of dental implants to replace missing teeth has been one of the most “exciting and evolving areas of clinical dentistry”this decade1. At a time when esthetic dentistry has gained prominence, permanent solutions such as implants have become optimal esthetic treatment options.1,2 While implants have expanded restorative treatment options, treatment planning has become more complex for the dental practitioner and an interdisciplinary team approach is recommended. 2,3 The need for replacing missing teeth involves an interdisciplinary approach with Orthodontist, Periodontist and Prosthodontist. 4 The prevalence of congenitally missing lateral incisor constitutes 5% of the population. It has also been found that the agenesis of both lateral incisors is more common than the agenesis of one lateral incisor (Stamation and Symons 1991). Females are found to be more affected than males (Bergstom 1977, Rolling 1980, Brook 1984, Aashem&Oganard 1993). Treatment alternatives for restoring edentulous spaces resulting from congenitally missing laterals include removable partial dentures, conventional fixed partial denture, resin-bonded bridges, repositioning of canines orthodontically to close the edentulous space and single-tooth implant. 5 Although adjacent teeth may have to be repositioned orthodontically to create space for an implant, implants do not necessitate “altering”or “removing”parts of the natural dentition and are therefore the most conservative options for replacing missing lateral incisors.5-7 In most instances due to the absence of the lateral incisor there is an absence of any functional stimulus for the alveolar expansion to occur resulting in a thin or knife edged alveolar ridge, which may not ideally support an implant. Ridge augmentation procedure is mandatory in many such situations, which can be performed before or during the placement of the implant as per the indication of the individual patient need. Implants can also maintain the alveolar ridge, enhance occlusal function and provide optimal esthetics. This procedure is more favourable since most of the patients are in the adolescent stage with good bone texture.5,8
Success of these implants depend on good evaluation and assessment of bone at the implant site. With hard and soft tissue grafting procedures that are available, implant prognosis rate as well as final esthetic outcome has become increasingly predictable.
CASE REPORT
A female patient aged 21 years, was found to have congenitally missing bilateral maxillary lateral incisors, with spacing between maxillary canine and central incisor, midline diastema was also evident due to tooth material deficiency.

A full set of orthodontic records comprising of study casts, radiographs and clinical photographs were taken for the routine investigation procedure. Participating clinicians (the Orthodontist, Periodontist, Prosthodontist) determined the patients treatment plan collaboratively and communicated throughout the course of the treatment to ensure all the aspects of the treatment are considered and the overall treatment objectives achieved.
The role of the Orthodontist is vital as the space needed for the implant placement in the lateral incisor had to be accurately assessed, by model analysis. The space needed had to be created, by closing the midline diastema, as well as the roots of the maxillary canine and maxillary incisors had to be up righted in order to avoid hindrance during implant placement. Ridge dimension needed for implant placement is 10 mm height and 6 mm width9. Adequate space for the implant is also required between the adjacent roots, ideally they should be parallel to each other. The golden proportion should be considered: one lateral incisor is equal to twothirds of a central incisor. Although, when implants are part of the treatment plan, their size dictates the amount of space that needs to be opened.
On examination, patient presented a pleasant profile and was classified as dento-alveolar class I malocclusion intra-orally, owing to which a nonextraction treatment strategy was adopted. The space required was estimated using Bolton’s analysis which is considered a reliable method. The estimated space for each lateral incisor was 5.9 mm. 0.022 MBT system was used to align and create the space that was calculated. Orthodontic treatment was carried out methodically followed by the prescribed sequence of wires. The permanent central incisors and canines were positioned ideally considering the appropriate root positions for the easy placement of the implant. The patient was under passive state oforthodontic treatment during placement of the implant.
IMPLANT PLACEMENT
Bone growth should be completed at the time of implant placement. Since the alveolar bone formation and adjacent teeth eruption continues there are chances of anterior open bite, if implant placement is done prior to completion ofalveolar bone growth. In this case, implants were placed 18 months after the commencement of orthodontic treatment and sufficient bone width was achieved for the implant. A computer tomography was taken to assess the amount of bone in the edentulous area. Transgingival probing was done prior to placement of implants which showed a width of bone in the upper left lateral incisor region to be 7 mm and upper right lateral incisor region to be 5 mm. Surgical templates were prepared to guide the placement of implants. The implant was placed bilaterally using an open flap technique. Two implants were placed, one with a diameter of 3.3 mm and length of 13mm and the other with the diameter of 3.3 mm and length of 11.5mm. After placing the implant, dehiscence was seen in relation to maxillary right incisor region. A bone graft [Bio-Oss] was placed over the implant along with a GTR membrane. The flap was sutured using 4-0 silk sutures. The appliance was consolidated and maintained in a passive state to promote good healing of the implant site.
DISCUSSION
The prevalence of congenitally missing lateral incisor constitutes 5% of the population. When there is a family history of congenitally missing teeth, asymmetric loss of primary teeth, over-retention of deciduous lateral incisors and canines, lack of developmental canine bulge or impacted maxillary canines, the possibility of missing lateral incisors should be immediately investigated. Early investigation is especially important due to the higher association of congenitally missing or peg-shaped lateral incisors with these anomalies. In addition, early investigation will give the patient time to explore all possible treatment options including implant restorations.

Psychological effects of tooth loss are complex and varied and range from minimal to a state of anxiety which significantly affects the social life. Studies done by Mahmoud K et al, 200910 demonstrated that females are more affected by tooth loss in terms of eating and body activity. The number of missing anterior teeth influences patient perception and satisfaction with their dentition. 80% of the patients treated with implant-supported prosthesis were judged for their  overall psychological health and showed improved psychological health compared with their previous state of wearing removable dentures or fixed prosthesis. Fixed prosthesis requires support from the adjacent teeth as well there is an increased risk of fracture, loosening or root sensitivity which is a major disadvantage.
Computerized tomography provides cross-sectional radiographic images that facilitate proper assessment of potential recipient sites for implant placement. It offers a precise and detailed evaluation of the height and width of alveolar ridge. The surgical placement of implants is governed primarily by the prosthetic design and secondarily by the morphology and quality of the alveolar bone. Implant placement may be difficult if at all possible due to alveolar ridge aberrations. In consequence, prosthetically dictated dental implant positioning often entails augmentation of the alveolar ridge and adjacent structures. Bio-Oss is a highly biocompatible and osteoconductive material which is slowly resorbed in humans and can be used with success as a bone substitute in ridge augmentation procedures.
CONCLUSION
This case report describes aesthetic and functional outcomes obtained by the multidisciplinary approach for the restoration of congenitally missing maxillary left and right lateral incisor areas and fabrication of two single crowns. In congenitally missing situations, in absence of any pathologic symptoms or negative radiologic findings, such a kind of treatment suggest a successful and a satisfactory result in short-term evaluation.

References:

1. Mantzikos T, Shamus I. Case report: forced eruption and implant site development. Angle Orthod 1996;68(2):179-86.
2. Schweizer CM, Schlegel AK, Rudzki-Janson I. Endosseous dental implants in orthodontic therapy. Int Dent J 1996;46(2):61-8.
3. Dialogue. The role of the orthodontist on the maxillary anterior implant team. Am AssocOrthodon 1998;10(2):67-9.
4. Bishara SE. Impacted maxillary canines: a review. Am J Orthod- DentofacialOrthop 1992;101(2):159-71.
5. Rupp RP, Dillehay JK, Squire CF. Orthodontics, Prosthodontics and Periodontics: a multidisciplinary approach. Gen Dent 1997;45(3):286-9.
6. Balshi TJ. Osseointegration and Orthodontics: modern treatment for congenitally missing teeth. Int J Perio Rest Dent 1993;13(6):495-5.
7. Cronin RJ, Cagna DR. An update on fixed prosthodontics. J Am Dent Assoc 1997;128(4):425-36.
8. Miller BJ, Taylor NG. Lateral thinking: the management of missing upper lateral incisors. Br Dent J 1995;79(3):99-106.
9. Spear FM, Mathews DM, Kokich VG. Interdisciplinary management of single-tooth implants. Semin Orthod. 1997;3(1):45–72.
10. Mahmoud K Al-Omiri, Jumana A Karasneh, Edward Lynch, Philip-John Lamey, Thomas J Clifford. Impact of missing upper anterior teeth on daily living. Int Dent J 2009;59(3):127-132.

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Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

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Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

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‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


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