International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
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IJCRR - Vol 02 Issue 04, April, 2010

Pages: 52-55

Date of Publication: 30-Nov--0001


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ANTI BACTERIAL ACTIVITY OF BARK EXTRACTS OF PTEROCARPUS MARSUPIUM ROXB.

Author: H.R.Ambujakshi

Category: General Sciences

Abstract:Anti bacterial activity of ethanol and water extracts of barks of Pterocrpus marsupium were tested by cup-plate agar diffusion method against Staphylococcus aureus, Bacillus sterothermophilus (Gram +ve) and Eschericia coli , Klebsiella pneumoniae (Gram -ve) bacteria. Ciprofloxacin was used as the standard. It was observed that all extracts have dose dependent inhibitory effect, ethanol extract being most effective.

Keywords: Antibacterial, Pterocrpus marsupium, cup-plate.

Full Text:

Pterocarpus marsupium Roxb.(Leguminosae) is also known as Indian Kino tree or Bijasar, is common in the hilly regions of central and peninsular india1 .The extracts of leaves, flowers and gum obtained from the stem of this tree have been used medicinally in the treatment of diarrhea, toothache, fever, urinary tract and skin infections2 .The extract of the bark has been regarded as useful in the therapy of diabetes3 .The aqueous extract of the stem bark was found to reduce the blood glucose level in alloxan - induced diabetic rats4 . The ethnic uses includes the use of stem bark of this species in treating wounds, fever, stomachache, diabetes and jaundice5 .The current study was undertaken to evaluate the antibacterial activity of ethanol and water extracts of Pterocarpus marsupium Ethanol and water extracts were tested against Staphylococcus aureus, Bacillus sterothermophilus (Gram +ve) and Eschericia coli , Klebsiella pneumoniae (Gram -ve). Ciprofloxacin was used as the standard

Materials and Methods Plant material

The fresh barks of Pterocarpus marsupium Roxb were collected from the Jeddu Ayurveda vanaspathi abivriddi parishat, Bantwal Taluk, D.K. District, Karnataka.

Extraction of plant material

The barks were dried under sunny condition at ambient temperature and then ground by using grinder, to coarse powder and the powder was packed in soxhlet column and extracted with ethanol for 24 hrs. Successively drug is boiled for 30min using distilled water. The extracts were concentrated under reduced pressure at 50 C using rotary evaporator to a powder mass, which was then stored at 40 C until used. Crude extract was subjected to preliminary phytochemical screening to characterize the phyto constituents present.

Screening for antibacterial activity

Antibacterial activity was tested by cup-plate agar diffusion method to determine the zone of inhibition of two extracts. The extracts were freshly reconstituted with suitable solvents (H2O / DMSO) tested at concentration of 800 and 400 g/ml against all the microorganisms. Ciprofloxacin (Himedia laboratories, Mumbai,) were separately dissolved in DMSO to give a concentration of Ciprofloxin 20 g/ml.

Sterile nutrient agar plates were prepared and 0.1 ml of 4he inoculums from standardized culture of test organism was spread uniformly. Wells were prepared by using a sterile borer of diameter 10mm and 100l of the test substance, standard antibiotic and the solvent control were added in each well separately. The plates were placed at 4 0C for 1 h to allow the diffusion of test solution into the medium and plates were incubated at 370C for 24 h and the zone of inhibition of microbial growth around the well was measured in mm.

Result and discussion:

Preliminary phytochemical studies revealed the presence of tannins, flavonoids and glycosides. From the zone of inhibition produced by the extracts, it was observed that a concentration dependent antibacterial activity was observed with both alcoholic and water extracts. The alcohol extract was more potent than water extract. The antimicrobial activity may be due to the presence of tannins. Other constituents like flavonoids may also contribute to the activity.

Acknowledgement:

Authors are thankful to Mr. Premnath Reddy, Chairman, Acharya & B.M. Reddy College of Pharmacy, Bangalore for providing laboratory facilities to carry out this project.

References:

1. Jain, S. K., Medicinal plants, National Book Trust, New Delhi, 1968, p.116

2. Chopra R N, Nayar SL, Chopra IC, Glossary of Indian medicinal plants. New Delhi: CSIR: 1956.

3. Kirtikar, K.R and Basu, B.D., Indian Medicinal plants, 2nd Ed., Delhi, India, 1975,272

4. Vats V. Grover Jk, Rathi SS., J. Ethnopharmacol.2002, 79, 95-100.

5. Mankni K.L, Krishna V, Manjunath B.K, Vidya S.M, Jagadeesh Singh S.D, Manohara Y.N, AneesurRaheman, Avinash k.R, Indian J Pharmacol. June 2005, 37, 3, 165-168

6. Ali Ms, Ahmad VU, Usmanghani K, Azhar I and Amtul Z.,Fitopteropia,1999, 70; 299-304

Research Incentive Schemes

Awards, Research and Publication incentive Schemes by IJCRR

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One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

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Best Article Award

A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Leow Jun Xian and Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh et al. entitled "Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma COLAKOGLU entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by Arpita M. et al entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09
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List of Awardees

Awardees of COVID-19 Research

Woman Researcher Award

A Study by Neha Garg et al. entitled "Optimization of the Response to nCOVID-19 Pandemic in Pregnant Women – An Urgent Appeal in Indian Scenario" published in Vol 12 issue 09

A Study by Sana Parveen and Shraddha Jain entitled "Pathophysiologic Enigma of COVID-19 Pandemic with Clinical Correlates" published in Vol 12 issue 13

A Study by Rashmi Jain et al. entitled "Current Consensus Review Article on Drugs and Biologics against nCOVID-19 – A Systematic Review" published in Vol 12 issue 09

Emerging Researcher Award

A Study by Madhan Jeyaraman et al. entitled "Vitamin-D: An Immune Shield Against nCOVID-19" published in Vol 12 issue 09

Study by Dheeraj Kumar Chopra et al. entitled "Lipid-Based Solid Dispersions of Azilsartan Medoxomil with Improved Oral Bioavailability: In Vitro and In Vivo Evaluation" published in Vol 12 issue 19


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