International Journal of Current Research and Review
ISSN: 2231-2196 (Print)ISSN: 0975-5241 (Online)
logo
slider
slider
slider
slider
Bootstrap Slider

Indexed and Abstracted in: Crossref, CAS Abstracts, Publons, Google Scholar, Open J-Gate, ROAD, Indian Citation Index (ICI), ResearchGATE, Ulrich's Periodicals Directory, WorldCat (World's largest network of library content and services)

Search Articles

Track manuscript

Full Html

IJCRR - 4(18), September, 2012

Pages: 54-59

Date of Publication: 29-Sep-2012


Print Article   Download XML  Download PDF

CYTOGENETIC EFFECT OF PHYTOPESTICIDE AGAINST LEPIDOPTERAN PESTS

Author: Maria Packiam S, Elumalai K, Ignacimuthu S

Category: General Sciences

Abstract:The present investigation aims to assess the cytogenetic effect of PONNEEM, a newly prepared botanical pesticide against the fourth instar larvae of Spodoptera litura Fab. PONNEEM exhibited spectacular changes in the morphological structure of chromosome of S. litura at 10 ppm concentration. The various karyomorphological changes namely metaphase plates showing clumping of chromosome, dots chromosome, endo reduplication, ploidy and deletion of chromosome were observed. This is the first report on the cytogenetic effect of PONNEEM against fourth instar larvae of S. litura. The severe damage on chromosome of S. litura was noticed due to the synergistic effect PONNEEM consisting of pongam and neem oils. So, this effective botanical pesticide which is safe and eco-friendly can be used as an alternative to chemical pesticides to control lepidopteran pests.

Keywords: Spodoptera litura, PONNEEM, Karyomorphology, Ploidy, Cytogenetic

Full Text:

INTRODUCTION
Karanjin which is the active principle obtained from the plant Karanj or Pungam tree.[1] More than 19 biologically active components have been identified from this plant. Karanj is reported to be effective in controlling insect pests of stored grains, field [2] and plantation crops. It acts as oviposition deterrent or antifeedant or insecticide [3] against insect pests [4]. Neem tree is a versatile tree containing large number of chemicals and biologically active compounds. At present more than 100 triterpenoids and a few non-isoprenoid constituents like phenolics, carbohydrates and proteins and sulphur compounds have been isolated from neem tree. Azadirachtin A was the first member isolated by Butterworth and Morgan [5] from neem seeds showing the antifeedant and insect growth inhibitor effects on Schistoereca greagaria. Due to the presence of bitterness in different parts of neem tree, it has emerged as an important source as well as an alternative for the synthetic insecticides. It is known for its diverse effects like repellency, feeding deterrencey, oviposition deterrencey and growth inhibitory action on insect pests.[6] The combination of pungam and neem oils (1:1 ratio) was named as 'PONNEEM'. PONNEEM was patented (Indian Patent No. 204381) by the Entomology Research Institute, Loyola College, Chennai, Tamil Nadu, India) because of higher bioactivities against field insect pests [7] . This present investigation was aimed at finding the impact of 'PONNEEM' on the chromosomes of Spodoptera litura which is a polyphagous insect pest [8] damaging more than 120 plant species.

METHODOLOGY
Insect Rearing
Egg masses of Spodoptera litura were collected from groundnut field at Vellavedu village near Poonamallee, Chennai. The eggs were surface sterilized with 0.02% sodium hypochlorite solution, dried and allowed to hatch. After hatching the neonate larvae were reared on castor leaves till pre pupal stage and sterilized soil was provided for pupation. The pupae were collected from the soil and kept in oviposition chambers (40 x 25 x 25 cm). After adult emergence, cotton soaked with 10% (w/v) sugar solution with multivitamin drops was provided for adult moths to increase the rate of fecundity. Petioles of fresh castor leaves inserted in conical flask containing water (to avoid early drying of the leaves) were provided for egg laying. After egg laying, the egg masses were collected from the leaves and surface sterilized with 0.02% sodium hypochlorite solution, dried and allowed to hatch. The fourth instar larvae reared in the laboratory were used for the present study.

Preparation of PONNEEM
Pongum and neem oils were taken at 1:1 ratio in a stainless steel vessel with a stirrer and were stirred at 120 rpm for 10 minutes. Then 8% emulsifier and 1% stabilizer were added to the oils and again it was stirred at 120 rpm for 10 minutes. At last 0.123% Azadirachtin and 2% isopropyl alcohol were added and again it was mixed thoroughly by using a stirrer at 120 rpm for 10 minutes. Then PONNEEM was obtained [9,10] .

Chromosomal Analysis
The larval sex organs (ovary and testes) of 10 ppm PONNEEM treated and control larvae of S. litura were dissected out in 0.001% Colchicine solution and were left in the same solution for 2.5 hours and then they were transferred to hypotonic solution (0.45% sodium citrate solution). After 30 minutes, it was replaced by fresh hypotonic solution and kept at room temperature for 30 minutes. At the end of 30 minutes, the tissue was transferred to a clean dry slide and a drop of acetic acid: methanol (1:3) mixture was added and squashed for a minute. Then the slides were freezed on dry ice for 2-3 minutes, thawed and kept in glacial acetic acid for 30 seconds and subsequently air dried for 45 minutes. The air dried slides were stained in Giemsa, diluted 30 times in Sorrenson’s phosphate buffer having pH 6.8, for 15 minutes at room temperature and then excess stain was de-stained in double distilled water and then the slides were air dried. The air dried slides were observed on the next day (Murakami and Imai, 1974)[11]. The various chromosomal aberrations in treated larvae of S. litura were observed under the microscope.

RESULTS
Damage on chromosome of S. litura
Effect of PONNEEM at 10 ppm concentration against larvae of S. litura was apparent in view of its cytogenetic effects. Fourth instar larvae exposed to such concentration were screened for chromosomal aberrations. Results clearly revealed that PONNEEM had significant effect in altering the genetic constitution of the target insect pest carrying reduction in the growth of larvae when compared to the untreated larvae (Figure 1).

Chromosomal aberrations like clumping of chromosome (Figure 2: A), condensation into dots (Figure 2 : B) were seen. Many metaphase plates showed chromosomal variation in number, though they had distinct morphology (Figure 2: C & D). Ploidy was the common phenomenon observed in all the experimental larvae (Figure 2: F).

DISCUSSION
Fourth instar larvae exposed to such concentration of phytopesticidal formulation have been screened for chromosomal aberrations. Several damages on chromosomes of S. litura were observed at 10 ppm concentration of PONNEEM. Chromosomal aberrations like clumping of chromosome, condensation into dots were seen. Many metaphase plates showed chromosomal variation in number, though they had distinct morphology. The present finding coincides with the findings of Maheswaran and Ignacimuthu [12] who noticed that PONNEEM showed remarkable ovicidal activity of against human vector mosquitoes Aedes aegypti and Aedes albopictus. Similarly Packiam and Ignacimuthu [15] noticed that PONNEEM treated larvae of S. litura had reduced egg hatchability when they emerged into adults. In the present investigation, PONNEEM exhibited the damage on chromosome of S. litura because of the synergistic effect of active compounds like azadirachtin (Fig. 3) and karanjin (Fig. 4). In an earlier report, neem oil based formulation of active fraction of ethyl acetate extract of Hydnocarpus alpine showed antifeedant activity against S. litura [16]. Pavunraj et al., [17] reported that effective fraction from Melochia corchorifolia with 1:1 ratio of neem and pongam showed antifeedant activity against four lepidopteran pests.

CONCLUSION PONNEEM
produced high damage on the chromosome of S. litura. It was highly toxic to lipodopteran insect pests in which internal cells were damaged, Its normal growth was arrested due to its synergistic activity. This is the first report on the cytogenetic effect of PONNEEM against S. litura. This effective phytopesticidal formulation can be a safe and alternate to chemical pesticides. This is also good for integrated pest management programme in agriculture.

ACKNOWLEDGEMENT
Authors acknowledge the immense help received from the scholars whose articles are cited and included in references of this manuscript. The authors are also grateful to authors / editors / publishers of all those articles, journals and books from where the literature for this article has been reviewed and discussed.

References:

1. Venugopala Verma SR, Gupta SP, Tyagi GP. Studies on the toxicity of lindane on Colisa fasciatus. Part I. TML measurement and histopathological changes in certain tissues. Gegenbaurs Morp Jahrp Leipzic. 1975; 121(1):38-54.

2. Kumar V, Chandrashekar K, Sidhu OP. Efficacy of karanjin and different extracts of Pongamia pinnata against selected insect pests. J Entomol Res. 2006; 30:103–108.

3. Kabir KE, Islam F, Khan AR. Insecticidal effect of the petroleum ether fraction obtained from the leaf extract of Pongamia glabra Vent. on the American cockroach, Periplaneta americana (L.) (Dictyoptera: Blattidae). Int Pest Control. 2001; 43:152–154.

4. Mukesh Kumar, Ram Singh M, Kumar, Singh R. Potential of Pongamia glabra vent as an insecticide of plant origin, Biological Agriculture and Horticulture. 2002; 20:29.

5. Butterworth JH and Morgan ED. Investigations of the locust feeding inhibition of the neem tree Azadirachta indica. J Insect Physiol. 1968; 17:969-977.

6. Harikrishnan R, Rani MN, Balasundaram C. Hematological and biochemical parameters in common carp, Cyprinus carpio, following treatment for Aeromonas hydrophila infection. Aquacult. 2003; 221: 41-50.

7. The patent office journal dated on 19/05/2006, visited on 20/07/2012 at http://www.tmpsearchers.com/Patdatabase/20 06May19/pg_0021.htm.

8. Baskar K, Antony Raj G, Murali Mohan P, Lingathurai S, Ambrose T, Muthu C. Larvicidal and Growth Inhibitory Activities of Entomopathogenic Fungus, Beauveria bassiana against Asian Army Worm, Spodoptera litura Fab. (Lepidoptera: Noctuidae). Journal of Entomology. 2012; 9(3):155-162.

9. Packiam SM, Ignacimuthu S. Effect of PONNEEM on Spodoptera litura (Fab.) and Its Compatibility with Trichogramma chilonis Ishii. Braz Arch Biol Technol. 2012; 22: 291- 298.

10. Packiam SM, Baskar, K, Ignacimuthu S. Ovicidal activity of botanical oil formulations against Helicoverpa armigera Hubner and Spodoptera litura Fabricius (Lepidoptera: Noctuidae). Asian J Tropical Biomed (In press). 2012.

11. Murakami A, and Imai HT. Cytological evidence for holocentric chromosomes of Bombyx mori L. and Bombyx mandarina M. (Bombycidae), Chromosoma, 1974; 47(2):167-178.

12. Maheswaran R, Ignacimuthu S. A novel herbal formulation against dengue vector mosquitoes Aedes aegypti and Aedes albopictus. Parasitol Res. 2012; 110:1801- 1813.

13. Butterworth, J.H. and Morgan, E.D. 1968, Isolation of a substance that suppresses feeding of locusts. Chemical Commun. 23-24.

14. Vismaya, Sapna Eipeson W, Manjunatha JR, Sriniva P, Sindhu Kanya TC. Extraction and recovery of karanjin: A value addition to karanja (Pongamia pinnata) seed oil. Industrial Crops and Products. 2010; 32(2): 118-122.

15. Packiam SM, Ignacimuthu S. ibid.

16. Vendan SE, Lingathurai S, Paulraj MG, Ignacimuthu S. Bioefficacy of neem oil formulation with Hydnocarpus alpina leaf extract against Spodoptera litura. Int J Curr Res. 2010; 3:78-82.

17. Pavunraj M, Baskar K, Ignacimuthu S. Efficacy of Melochia corchorifolia L. (Sterculiaceae) on Feeding Behavior of Four Lepidopteran Pests. Int J Agric Res. 2012; 7: 58-68.

A. Metaphase plates showing clumping of chromosome
B. Photomicrograph showing dots chromosome, endo reduplication and ploidy nature
C. Metaphase plate showing rods and dots like chromosomes. Arrow indicates deletion of chromosome. Encircled chromosome indicates attachment of a fragment (addition of chromosome)
D. Metaphase plate showing rods and dots like chromosomes. Arrow indicates deletion of chromosome. Encircled chromosome indicates attachment of a fragment (addition of chromosome)
E. Ploidy Chromosomes with distinct morphology

Announcements

Dr. Pramod Kumar Manjhi joined Editor-in-Chief since July 2021 onwards

COPE guidelines for Reviewers

SCOPUS indexing: 2014, 2019 to 2021


Awards, Research and Publication incentive Schemes by IJCRR

Best Article Award: 

One article from every issue is selected for the ‘Best Article Award’. Authors of selected ‘Best Article’ are rewarded with a certificate. IJCRR Editorial Board members select one ‘Best Article’ from the published issue based on originality, novelty, social usefulness of the work. The corresponding author of selected ‘Best Article Award’ is communicated and information of award is displayed on IJCRR’s website. Drop a mail to editor@ijcrr.com for more details.

Women Researcher Award:

This award is instituted to encourage women researchers to publish her work in IJCRR. Women researcher, who intends to publish her research work in IJCRR as the first author is eligible to apply for this award. Editorial Board members decide on the selection of women researchers based on the originality, novelty, and social contribution of the research work. The corresponding author of the selected manuscript is communicated and information is displayed on IJCRR’s website. Under this award selected women, the author is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.

Emerging Researcher Award:

‘Emerging Researcher Award’ is instituted to encourage student researchers to publish their work in IJCRR. Student researchers, who intend to publish their research or review work in IJCRR as the first author are eligible to apply for this award. Editorial Board members decide on the selection of student researchers for the said award based on originality, novelty, and social applicability of the research work. Under this award selected student researcher is eligible for publication incentives. Drop a mail to editor@ijcrr.com for more details.


Best Article Award

A study by Dorothy Ebere Adimora et al. entitled \"Remediation for Effects of Domestic Violence on Psychological well-being, Depression and Suicide among Women During COVID-19 Pandemic: A Cross-cultural Study of Nigeria and Spain\" is awarded Best Article of Vol 14 issue 23
A study by Muhas C. et al. entitled \"Study on Knowledge & Awareness About Pharmacovigilance Among Pharmacists in South India\" is awarded Best article for Vol 14 issue 22
A study by Saurabh Suvidha entitled \"A Case of Mucoid Degeneration of Uterine Fibroid with Hydrosalphinx and Ovarian Cyst\" is awarded Best article of Vol 14 issue 21
A study by Alice Alice entitled \"Strengthening of Human Milk Banking across South Asian Countries: A Next Step Forward\" is awarded Best article of Vol 14 issue 20
A study by Sathyanarayanan AR et al. entitled \"The on-task Attention of Individuals with Autism Spectrum Disorder-An Eye Tracker Study Using Auticare\" is awarded Best article of Vol 14 issue 19
A study by Gupta P. et al. entitled \"A Short Review on \"A Novel Approach in Fast Dissolving Film & their Evaluation Studies\" is awarded Best Article of Vol 14 issue 18.
A study by Shafaque M. et al. entitled \"A Case-Control Study Performed in Karachi on Inflammatory Markers by Ciprofloxacin and CoAmoxicillin in Patients with Chronic Suppurative Otitis Media\" is awarded Best Article of Vol 14 issue 17
A study by Ali Nawaz et al. entitled \"A Comparative Study of Tubeless versus Standard Percutaneous Nephrolithotomy (PCNL) \? A Randomized Controlled Study\" is awarded Best Article for Vol 14 issue 16.
A study by Singh R. et al. entitled \"A Prospective Study to Find the Association of Astigmatism in Patients of Vernal Keratoconjunctivitis (VKC) in a Tertiary Health Care Centre in India (Vindhya Region MP)\" is awarded Best Article for Vol 14 issue 15
A Study by Humaira Tahir et al. entitled "Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study" is awarded Best Article for Vol 14 issue 14
A Study by Monica K. entitled "Risk Predictors for Lymphoma Development in Sjogren Syndrome - A Systematic Review" is awarded Best Article for Vol 14 issue 13
A Study by Mokhtar M Sh et al. entitled "Prevalence of Hospital Mortality of Critically Ill Elderly Patients" is awarded Best Article for Vol 14 issue 12
A Study by Vidya S. Bhat et al. entitled "Effect of an Indigenous Cleanser on the Microbial Biofilm on Acrylic Denture Base - A Pilot Study" is awarded Best Article for Vol 14 issue 11
A Study by Pandya S. et al. entitled "Acute and 28-Day Repeated Dose Subacute Toxicological Evaluation of Coroprotect Tablet in Rodents" is awarded Best Article for Vol 14 issue 10
A Study by Muhammad Zaki et al. entitled "Effect of Hemoglobin Level on the Severity of Acute Bronchiolitis in Children: A Case-Control Study" is awarded Best Article for Vol 14 issue 09
A Study by Vinita S & Ayushi S entitled "Role of Colour Doppler and Transvaginal Sonography for diagnosis of endometrial pathology in women presenting with Abnormal Uterine Bleeding" is awarded Best Article for Vol 14 issue 08
A Study by Prabhu A et al. entitled "Awareness of Common Eye Conditions among the ASHA (Accredited Social Health Activist) Workers in the Rural Communities of Udupi District- A Pilot Study" is awarded Best Article for Vol 14 issue 07
A Study by Divya MP et al. entitled "Non-Echoplanar Diffusion-Weighted Imaging and 3D Fiesta Magnetic Resonance Imaging Sequences with High Resolution Computed Tomography Temporal Bone in Assessment and Predicting the Outcome of Chronic Suppurative Otitis Media with Cholesteatoma" is awarded Best Article for Vol 14 issue 06
A Study by Zahoor Illahi Soomro et al. entitled "Functional Outcomes of Fracture Distal Radius after Fixation with Two Different Plates: A Retrospective Comparative Study" is awarded Best Article for Vol 14 issue 05
A Study by Ajai KG & Athira KN entitled "Patients’ Gratification Towards Service Delivery Among Government Hospitals with Particular Orientation Towards Primary Health Centres" is awarded Best Article for Vol 14 issue 04
A Study by Mbungu Mulaila AP et al. entitled "Ovarian Pregnancy in Kindu City, D.R. Congo - A Case Report" is awarded Best Article for Vol 14 issue 03
A Study by Maryam MJ et al. entitled "Evaluation Serum Chemerin and Visfatin Levels with Rheumatoid Arthritis: Possible Diagnostic Biomarkers" is awarded Best Article for Vol 14 issue 02
A Study by Shanthan KR et al. entitled "Comparison of Ultrasound Guided Versus Nerve Stimulator Guided Technique of Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Surgeries" is awarded Best Article for Vol 14 issue 01
A Study by Amol Sanap et al. entitled "The Outcome of Coxofemoral Bypass Using Cemented Bipolar Hemiarthroplasty in the Treatment of Unstable Intertrochanteric Fracture of Femur in a Rural Setup" is awarded Best Article Award of Vol 13 issue 24
A Study by Manoj KP et al. entitled "A Randomized Comparative Clinical Trial to Know the Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block Against Multimodal Analgesia for Postoperative Analgesia Following Caesarean Section" is awarded Best Article Award of Vol 13 issue 23
A Study by Karimova II et al. entitled "Changes in the Activity of Intestinal Carbohydrases in Alloxan-Induced Diabetic Rats and Their Correction with Prenalon" is awarded Best Article of Vol 13 issue 22
A Study by Ashish B Roge et al. entitled "Development, Validation of RP-HPLC Method and GC MS Analysis of Desloratadine HCL and It’s Degradation Products" is awarded Best Article of Vol 13 issue 21
A Study by Isha Gaurav et al. entitled "Association of ABO Blood Group with Oral Cancer and Precancer – A Case-control Study" is awarded Best Article for Vol 13 issue 20
A Study by Amr Y. Zakaria et al. entitled "Single Nucleotide Polymorphisms of ATP-Binding Cassette Gene(ABCC3 rs4793665) affect High Dose Methotrexate-Induced Nephrotoxicity in Children with Osteosarcoma" is awarded Best Article for Vol 13 issue 19
A Study by Kholis Ernawati et al. entitled "The Utilization of Mobile-Based Information Technology in the Management of Dengue Fever in the Community Year 2019-2020: Systematic Review" is awarded Best Article for Vol 13 issue 18
A Study by Bhat Asifa et al. entitled "Efficacy of Modified Carbapenem Inactivation Method for Carbapenemase Detection and Comparative Evaluation with Polymerase Chain Reaction for the Identification of Carbapenemase Producing Klebsiella pneumonia Isolates" is awarded Best Article for Vol 13 issue 17
A Study by Gupta R. et al. entitled "A Clinical Study of Paediatric Tracheostomy: Our Experience in a Tertiary Care Hospital in North India" is awarded Best Article for Vol 13 issue 16
A Study by Chandran Anand et al. entitled "A Prospective Study on Assessment of Quality of Life of Patients Receiving Sorafenib for Hepatocellular Carcinoma" is awarded Best article for Vol 13 issue 15
A Study by Rosa PS et al. entitled "Emotional State Due to the Covid – 19 Pandemic in People Residing in a Vulnerable Area in North Lima" is awarded Best Article for Vol 13 issue 14
A Study by Suvarna Sunder J et al. entitled "Endodontic Revascularization of Necrotic Permanent Anterior Tooth with Platelet Rich Fibrin, Platelet Rich Plasma, and Blood Clot - A Comparative Study" is awarded Best Article for Vol 13 issue 13
A Study by Mona Isam Eldin Osman et al. entitled "Psychological Impact and Risk Factors of Sexual Abuse on Sudanese Children in Khartoum State" is awarded Best Article for Vol 13 issue 12
A Study by Khaw Ming Sheng & Sathiapriya Ramiah entitled "Web Based Suicide Prevention Application for Patients Suffering from Depression" is awarded Best Article for Vol 13 issue 11
A Study by Purushottam S. G. et al. entitled "Development of Fenofibrate Solid Dispersions for the Plausible Aqueous Solubility Augmentation of this BCS Class-II Drug" is awarded Best article for Vol 13 issue 10
A Study by Kumar S. et al. entitled "A Study on Clinical Spectrum, Laboratory Profile, Complications and Outcome of Pediatric Scrub Typhus Patients Admitted to an Intensive Care Unit from a Tertiary Care Hospital from Eastern India" is awarded Best Article for Vol 13 issue 09
A Study by Mardhiah Kamaruddin et al. entitled "The Pattern of Creatinine Clearance in Gestational and Chronic Hypertension Women from the Third Trimester to 12 Weeks Postpartum" is awarded Best Article for Vol 13 issue 08
A Study by Sarmila G. B. et al. entitled "Study to Compare the Efficacy of Orally Administered Melatonin and Clonidine for Attenuation of Hemodynamic Response During Laryngoscopy and Endotracheal Intubation in Gastrointestinal Surgeries" is awarded Best Article for Vol 13 issue 07
A Study by M. Muthu Uma Maheswari et al. entitled "A Study on C-reactive Protein and Liver Function Tests in Laboratory RT-PCR Positive Covid-19 Patients in a Tertiary Care Centre – A Retrospective Study" is awarded Best Article of Vol 13 issue 06 Special issue Modern approaches for diagnosis of COVID-19 and current status of awareness
A Study by Gainneos PD et al. entitled "A Comparative Evaluation of the Levels of Salivary IgA in HIV Affected Children and the Children of the General Population within the Age Group of 9 – 12 Years – A Cross-Sectional Study" is awarded Best Article of Vol 13 issue 05 Special issue on Recent Advances in Dentistry for better Oral Health
A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" is awarded Best Article of Vol 13 issue 06
A Study by Chen YY and Ghazali SRB entitled "Lifetime Trauma, posttraumatic stress disorder Symptoms and Early Adolescence Risk Factors for Poor Physical Health Outcome Among Malaysian Adolescents" is awarded Best Article of Vol 13 issue 04 Special issue on Current Updates in Plant Biology to Medicine to Healthcare Awareness in Malaysia
A Study by Kumari PM et al. entitled "Study to Evaluate the Adverse Drug Reactions in a Tertiary Care Teaching Hospital in Tamilnadu - A Cross-Sectional Study" is awarded Best Article for Vol 13 issue 05
A Study by Anu et al. entitled "Effectiveness of Cytological Scoring Systems for Evaluation of Breast Lesion Cytology with its Histopathological Correlation" is awarded Best Article of Vol 13 issue 04
A Study by Sharipov R. Kh. et al. entitled "Interaction of Correction of Lipid Peroxidation Disorders with Oxibral" is awarded Best Article of Vol 13 issue 03
A Study by Tarek Elwakil et al. entitled "Led Light Photobiomodulation Effect on Wound Healing Combined with Phenytoin in Mice Model" is awarded Best Article of Vol 13 issue 02
A Study by Mohita Ray et al. entitled "Accuracy of Intra-Operative Frozen Section Consultation of Gastrointestinal Biopsy Samples in Correlation with the Final Histopathological Diagnosis" is awarded Best Article for Vol 13 issue 01
A Study by Badritdinova MN et al. entitled "Peculiarities of a Pain in Patients with Ischemic Heart Disease in the Presence of Individual Combines of the Metabolic Syndrome" is awarded Best Article for Vol 12 issue 24
A Study by Sindhu Priya E S et al. entitled "Neuroprotective activity of Pyrazolone Derivatives Against Paraquat-induced Oxidative Stress and Locomotor Impairment in Drosophila melanogaster" is awarded Best Article for Vol 12 issue 23
A Study by Habiba Suhail et al. entitled "Effect of Majoon Murmakki in Dysmenorrhoea (Usre Tams): A Standard Controlled Clinical Study" is awarded Best Article for Vol 12 issue 22
A Study by Ghaffar UB et al. entitled "Correlation between Height and Foot Length in Saudi Population in Majmaah, Saudi Arabia" is awarded Best Article for Vol 12 issue 21
A Study by Siti Sarah Binti Maidin entitled "Sleep Well: Mobile Application to Address Sleeping Problems" is awarded Best Article for Vol 12 issue 20
A Study by Avijit Singh"Comparison of Post Operative Clinical Outcomes Between “Made in India” TTK Chitra Mechanical Heart Valve Versus St Jude Mechanical Heart Valve in Valve Replacement Surgery" is awarded Best Article for Vol 12 issue 19
A Study by Sonali Banerjee and Mary Mathews N. entitled "Exploring Quality of Life and Perceived Experiences Among Couples Undergoing Fertility Treatment in Western India: A Mixed Methodology" is awarded Best Article for Vol 12 issue 18
A Study by Jabbar Desai et al. entitled "Prevalence of Obstructive Airway Disease in Patients with Ischemic Heart Disease and Hypertension" is awarded Best Article for Vol 12 issue 17
A Study by Juna Byun et al. entitled "Study on Difference in Coronavirus-19 Related Anxiety between Face-to-face and Non-face-to-face Classes among University Students in South Korea" is awarded Best Article for Vol 12 issue 16
A Study by Sudha Ramachandra & Vinay Chavan entitled "Enhanced-Hybrid-Age Layered Population Structure (E-Hybrid-ALPS): A Genetic Algorithm with Adaptive Crossover for Molecular Docking Studies of Drug Discovery Process" is awarded Best article for Vol 12 issue 15
A Study by Varsha M. Shindhe et al. entitled "A Study on Effect of Smokeless Tobacco on Pulmonary Function Tests in Class IV Workers of USM-KLE (Universiti Sains Malaysia-Karnataka Lingayat Education Society) International Medical Programme, Belagavi" is awarded Best article of Vol 12 issue 14, July 2020
A study by Amruta Choudhary et al. entitled "Family Planning Knowledge, Attitude and Practice Among Women of Reproductive Age from Rural Area of Central India" is awarded Best Article for special issue "Modern Therapeutics Applications"
A study by Raunak Das entitled "Study of Cardiovascular Dysfunctions in Interstitial Lung Diseas epatients by Correlating the Levels of Serum NT PRO BNP and Microalbuminuria (Biomarkers of Cardiovascular Dysfunction) with Echocardiographic, Bronchoscopic and HighResolution Computed Tomography Findings of These ILD Patients" is awarded Best Article of Vol 12 issue 13 
A Study by Kannamani Ramasamy et al. entitled "COVID-19 Situation at Chennai City – Forecasting for the Better Pandemic Management" is awarded best article for  Vol 12 issue 12
A Study by Muhammet Lutfi SELCUK and Fatma entitled "Distinction of Gray and White Matter for Some Histological Staining Methods in New Zealand Rabbit's Brain" is awarded best article for  Vol 12 issue 11
A Study by Anamul Haq et al. entitled "Etiology of Abnormal Uterine Bleeding in Adolescents – Emphasis Upon Polycystic Ovarian Syndrome" is awarded best article for  Vol 12 issue 10
A Study by entitled "Estimation of Reference Interval of Serum Progesterone During Three Trimesters of Normal Pregnancy in a Tertiary Care Hospital of Kolkata" is awarded best article for  Vol 12 issue 09
A Study by Ilona Gracie De Souza & Pavan Kumar G. entitled "Effect of Releasing Myofascial Chain in Patients with Patellofemoral Pain Syndrome - A Randomized Clinical Trial" is awarded best article for  Vol 12 issue 08
A Study by Virendra Atam et. al. entitled "Clinical Profile and Short - Term Mortality Predictors in Acute Stroke with Emphasis on Stress Hyperglycemia and THRIVE Score : An Observational Study" is awarded best article for  Vol 12 issue 07
A Study by K. Krupashree et. al. entitled "Protective Effects of Picrorhizakurroa Against Fumonisin B1 Induced Hepatotoxicity in Mice" is awarded best article for issue Vol 10 issue 20
A study by Mithun K.P. et al "Larvicidal Activity of Crude Solanum Nigrum Leaf and Berries Extract Against Dengue Vector-Aedesaegypti" is awarded Best Article for Vol 10 issue 14 of IJCRR
A study by Asha Menon "Women in Child Care and Early Education: Truly Nontraditional Work" is awarded Best Article for Vol 10 issue 13
A study by Deep J. M. "Prevalence of Molar-Incisor Hypomineralization in 7-13 Years Old Children of Biratnagar, Nepal: A Cross Sectional Study" is awarded Best Article for Vol 10 issue 11 of IJCRR
A review by Chitra et al to analyse relation between Obesity and Type 2 diabetes is awarded 'Best Article' for Vol 10 issue 10 by IJCRR. 
A study by Karanpreet et al "Pregnancy Induced Hypertension: A Study on Its Multisystem Involvement" is given Best Paper Award for Vol 10 issue 09

List of Awardees

A Study by Ese Anibor et al. "Evaluation of Temporomandibular Joint Disorders Among Delta State University Students in Abraka, Nigeria" from Vol 13 issue 16 received Emerging Researcher Award


A Study by Alkhansa Mahmoud et al. entitled "mRNA Expression of Somatostatin Receptors (1-5) in MCF7 and MDA-MB231 Breast Cancer Cells" from Vol 13 issue 06 received Emerging Researcher Award


RSS feed

Indexed and Abstracted in


Antiplagiarism Policy: IJCRR strongly condemn and discourage practice of plagiarism. All received manuscripts have to pass through "Plagiarism Detection Software" test before Toto Macau forwarding for peer review. We consider "Plagiarism is a crime"

IJCRR Code of Conduct: To achieve a high standard of publication, we adopt Good Publishing Practices (updated in 2022) which are inspired by guidelines provided by Committee on Publication Ethics (COPE), Open Access Scholarly Publishers Association (OASPA) and International Committee of Medical Journal Editors (ICMJE)

Disclaimer: International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal.



ABOUT US

International Journal of Current Research and Review (IJCRR) provides platform for researchers to publish and discuss their original research and review work. IJCRR can not be held responsible for views, opinions and written statements of researchers published in this journal

Contact

148, IMSR Building, Ayurvedic Layout,
        Near NIT Complex, Sakkardara,
        Nagpur-24, Maharashtra State, India

editor@ijcrr.com

editor.ijcrr@gmail.com


Copyright © 2024 IJCRR. Specialized online journals by ubijournal .Website by Ubitech solutions